Horizon Health: Flavivirus Antibody Therapies
Funds €9–10M projects that turn monoclonal antibodies into prevention and treatment options for one Flavivirus.
Emerging and re-emerging viral infections can become global health threats quickly, especially as climate change alters where viruses spread. This topic funds research that moves existing monoclonal antibody candidates closer to prevention and treatment.
A proposal must choose one Flavivirus and stay focused on it. The work can complete laboratory characterisation, test protective effects in anim…
Advance existing prophylactic and therapeutic monoclonal antibody candidates against exactly one named Flavivirus: Dengue, Tick-borne Encephalitis, Japanese Encephalitis, West Nile Fever, Yellow Fever or Zika. Work covers in-vitro characterisation, animal-model protection testing, antibody-dependent enhancement risk, GMP batch production and first-in-human clinical safety studies. Proposals should engage regulators, use relevant research infrastructures and address sex, age, ethnicity and disability in clinical work.
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Guides for this application
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