DPFS Stage Two
Supports United Kingdom translational medicine teams through DPFS stage-two funding for disease-focused innovation.
The Developmental Pathway Funding Scheme (DPFS) Stage Two is the Medical Research Council's flagship invite-only translational funding instrument, supporting academically-led projects developing novel therapeutics, medical devices, diagnostics, and other health interventions from early development through phase 2a clinical trials. Stage Two is accessible only to applicants who received a formal inβ¦
Academically-led translational development of novel therapeutics, medical devices, diagnostics, and other health interventions from early development through phase 2a clinical trials.
Sign up free to see the funding breakdown
Sign up free to see the industries in scope
Sign up free to see the full eligibility
Sign up free to see how to apply
Sign up free to see what you submit
Sign up free to see the timeline
Sign up free to see where teams trip up
Guides for this application
All guides βGrants for Biotech Startups: NIH, NSF, SBIR/STTR, and Non-Dilutive Funding
A practical guide to grants for biotech startups, including NIH SBIR/STTR, NSF, translational funding, evidence, regulatory readiness, and budgets.
BudgetGrant Financials and Co-Funding Evidence: Examples for Startup Applications
See examples of grant financials, match funding evidence, co-funding tables, accountant letters, investor commitments, and budget-to-work-plan checks.
DocumentsGrant Work Plan Template: Work Packages, Gantt, Milestones, and Risks
Use this grant work plan template to structure work packages, tasks, owners, deliverables, Gantt timing, dependencies, and risk registers.
Write proposalGrant Concept Note Example: Pre-Proposal Structure for Startups
See a practical grant concept note example, with a worked deeptech pre-proposal, section map, invite-to-full logic, and reviewer checks.
More from MRC
All grants from this funder βCollaborate with the UK Human Functional Genomics Initiative
π¬π§MRC Β· United Kingdom
Test an academic-industry functional-genomics idea and generate early data.
UKRI translation: MRC proof of concept: stage two
π¬π§MRC Β· United Kingdom
Funding for invited academic-led translational health projects.
MRC Equip
π¬π§MRC Β· United Kingdom
Supports research equipment investments that expand laboratory capacity and strengthen translational health innovation.
UKRI Translation: MRC Impact Acceleration Awards
π¬π§MRC Β· United Kingdom
Single-step support for high-risk medical product development.
UKRI Translation: MRC Proof of Concept: stage one
π¬π§MRC Β· United Kingdom
Funding for academic-led development of novel health interventions.
UK Obesity Research Institute: full application
π¬π§MRC Β· United Kingdom
Establish a collaborative institute for mechanistic obesity research.
Similar grants
Browse the directory βSPRIND Recoding Medicine Challenge β Stage 1
π©πͺSPRIND Β· Germany
Funds teams that curate a valuable health dataset and prove its worth with a working AI application.
Diabetes UK PhD Studentships
π¬π§Diabetes UK Β· United Kingdom
Funds United Kingdom doctoral candidates through diabetes-focused PhD studentships for translational science careers.
BBSRC Stand-alone LINK β Always Open
π¬π§BBSRC Β· United Kingdom
Supports United Kingdom university and industry teams through LINK grants that share innovation ownership and risk.
Sir George Alberti Research Training Fellowship
π¬π§Diabetes UK Β· United Kingdom
Helps students and early career scholars with mentoring support for Sir George Alberti Research Training Fellowship in medical technology and biotechnology.
Scottish Enterprise R&D Grant
π¬π§Scottish Enterprise Β· United Kingdom
Funds Scottish firms through Scottish Enterprise grants to develop new products, processes, and services.
Strathclyde Inspire Accelerator
π¬π§Strathclyde Inspire Β· United Kingdom
Supports University of Strathclyde ventures through an accelerator that helps teams progress to investor-ready, mentor-backed operations.