Hoffman ALS Clinical Trial Awards
Funds clinical trial development for ALS interventions in early development phases.
The Hoffman ALS Clinical Trial Awards Program is an annual initiative of The ALS Association, the largest philanthropic funder of ALS research in the world, which has committed over $162 million to nearly 600 projects since 2014. The program de-risks early-stage clinical development by providing up to $1,000,000 in total funding over two or three years to support phase 1 or phase 2a biomarker-drivโฆ
Phase 1 or 2a biomarker-driven clinical trials of novel or repurposed therapeutics for ALS, including disease-modifying, symptomatic, and imaging-tracer approaches. Particular interest in TDP-43 and protein aggregation programs.
Sign up free to see the funding breakdown
Sign up free to see the industries in scope
Sign up free to see the full eligibility
Sign up free to see how to apply
Sign up free to see what you submit
Sign up free to see the timeline
Sign up free to see what winners did
Sign up free to see where teams trip up
Guides for this application
All guides โGrants for Biotech Startups: NIH, NSF, SBIR/STTR, and Non-Dilutive Funding
A practical guide to grants for biotech startups, including NIH SBIR/STTR, NSF, translational funding, evidence, regulatory readiness, and budgets.
Start hereTRL Levels Explained for Deeptech Founders
Learn what TRL levels mean, how to estimate technology readiness, and how TRL affects grants, EIC Accelerator, SBIR/STTR, funding stage, and application evidence.
DocumentsGrant Work Plan Template: Work Packages, Gantt, Milestones, and Risks
Use this grant work plan template to structure work packages, tasks, owners, deliverables, Gantt timing, dependencies, and risk registers.
Submit & reportGrant Reporting Requirements: Post-Award Reports and Compliance
Learn what grant reporting requirements cover, how financial and performance reports work, what to track after an award, and how to avoid post-award compliance mistakes.
More from ALS Association
All grants from this funder โClinical Research Training Scholarship in ALS
๐บ๐ธALS Association ยท United States
Supports clinician-scientists pursuing ALS studies through dedicated scholarship funding to strengthen real-world implementation.
Milton Safenowitz Postdoctoral Fellowship
๐บ๐ธALS Association ยท United States
Supports junior ALS postdocs through research fellowships to strengthen real-world implementation.
Richard Olney Clinician-Scientist Development Award in ALS
๐บ๐ธALS Association ยท United States
Supports clinician-scientists advancing ALS research through sustained development awards to strengthen real-world implementation.
Similar grants
Browse the directory โINCLUDE Project โ Clinical Trials Phased Awards
๐บ๐ธNICHD ยท United States
Funds phased clinical research programs for Down syndrome interventions through developmental and expansion awards.
ARO MURI
๐บ๐ธARO ยท United States
Supports multidisciplinary university teams pursuing long-range defense research collaborations and shared outcomes.
NCATS STTR Phase II
๐บ๐ธNCATS ยท United States
Funds U.S. small businesses and their nonprofit research partners to continue and expand translational R&D begun in STTR Phase I toward a commercial product.
NIMHD Parent SBIR Grant
๐บ๐ธNIMHD ยท United States
Funds United States small businesses developing health-disparities technologies through NIH SBIR grants.
NIMHD Parent STTR Grant
๐บ๐ธNIMHD ยท United States
Funds United States small businesses partnering with nonprofit research institutions on health-disparities technologies.
NEI SBIR Phase II โ R&D
๐บ๐ธNEI ยท United States
Supports United States. small businesses scaling vision concepts into full development pathways.