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Hoffman ALS Clinical Trial Awards Program

Hoffman ALS Clinical Trial Awards

Funds clinical trial development for ALS interventions in early development phases.

Between cyclesThe ALS AssociationUnited States

The Hoffman ALS Clinical Trial Awards Program is an annual initiative of The ALS Association, the largest philanthropic funder of ALS research in the world, which has committed over $162 million to nearly 600 projects since 2014. The program de-risks early-stage clinical development by providing up to $1,000,000 in total funding over two or three years to support phase 1 or phase 2a biomarker-driv…

Phase 1 or 2a biomarker-driven clinical trials of novel or repurposed therapeutics for ALS, including disease-modifying, symptomatic, and imaging-tracer approaches. Particular interest in TDP-43 and protein aggregation programs.

CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.Annual
Next deadlineiThe next date applications are due. Rolling means you can apply any time.—
Decision timeiTypical time from the deadline to the funder's decision.26 weeks
Project durationiHow long the funded work is expected to run.24–36 months
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.0%
Funding pooliThe total budget available across all awards in this round.—

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Last verified: 24 Jul 2026Source: www.als.org