DOE SBIR/STTR ASCR Topics
Offers innovation teams support in advanced computing and hardware-oriented technologies.
The DOE Office of Science Advanced Scientific Computing Research (ASCR) program contributes annual topic areas to the DOE Small Business Innovation Research and Small Business Technology Transfer (SBIR/STTR) program, which is managed by the DOE Office of Technology Commercialization (OTC) following a consolidation effective April 28, 2026. ASCR's recurring topic areas cover high-performance comput…
SBIR/STTR Phase I and II awards for US small businesses developing HPC software infrastructure, quantum computing, AI for science, and high-speed scientific networking aligned with ASCR topic areas.
Sign up free to see the funding breakdown
Sign up free to see the industries in scope
Sign up free to see the full eligibility
Sign up free to see how to apply
Sign up free to see the timeline
Sign up free to see where teams trip up
Guides for this application
All guides →SBIR/STTR Grants for Deeptech Startups
A practical guide to SBIR and STTR grants for deeptech startups, including agency fit, Phase I and II logic, eligibility, budgets, and review criteria.
Start hereCommercialization Plan for SBIR and Deeptech Grants
Learn how to write a commercialization plan for SBIR and deeptech grants, with market, IP, regulatory, customer, milestone, and funding sections.
Submit & reportSAM.gov Registration and UEI Guide for Federal Grant Applicants
Learn how SAM.gov registration, UEI numbers, Grants.gov accounts, organization profiles, workspace roles, and renewal timing fit together.
BudgetBudget Narrative Example for Grant Proposals
See how to write a grant budget narrative with line-item examples, a template structure, weak vs strong wording, and reviewer-facing cost logic.
More from DOE ASCR
All grants from this funder →INCITE Allocation Cycle
DOE ASCR · United States
Runs research teams and institutions for INCITE Allocation in artificial intelligence, quantum systems, and energy systems.
DOE Early Career Research Program — ASCR Track
🇺🇸DOE ASCR · United States
Supports grants for early career academic and lab researchers in advanced computing quantum and applied mathematics.
Genesis Mission: Transforming Science and Energy with AI
🇺🇸DOE ASCR · United States
Supports teams developing artificial intelligence for scientific discovery and energy applications through a two-step federal process.
Similar grants
Browse the directory →NSF SBIR/STTR Fast-Track Pilot
🇺🇸NSF · United States
Supports United States deep-tech startups through a combined early and continuation development route.
NSF SBIR Phase II
🇺🇸NSF · United States
Funds United States deep-tech startups extending proven early projects into substantial technology development.
NSF STTR Phase II
🇺🇸NSF · United States
Funds United States deep-tech projects that continue with nonprofit research partners after successful initial feasibility work.
DoD SBIR/STTR
🇺🇸DoD · United States
Supports small business and non-traditional teams across defense components in a shared topic flow.
DURIP (AFOSR)
🇺🇸AFOSR · United States
Supports United States universities acquiring major research equipment for defense-relevant research capabilities.
ARO MURI
🇺🇸ARO · United States
Supports multidisciplinary university teams pursuing long-range defense research collaborations and shared outcomes.