DOE SBIR/STTR — Seed
Invests in teams advancing energy, climate, and manufacturing innovation projects.
The DOE Small Business Innovation Research and Small Business Technology Transfer (SBIR/STTR) program, now managed by the DOE Office of Technology Commercialization following a consolidation effective April 28, 2026, provides competitive non-dilutive grants to U.S. small businesses developing innovative energy technologies. The program is authorized through FY2031 under the Small Business Innovati…
Energy R&D innovations by U.S. small businesses across DOE topic areas, funded through competitive non-dilutive Phase I (up to $250K) and Phase II (up to $1.6M) grants.
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Guides for this application
All guides →SBIR/STTR Grants for Deeptech Startups
A practical guide to SBIR and STTR grants for deeptech startups, including agency fit, Phase I and II logic, eligibility, budgets, and review criteria.
Where to applyGrants for Biotech Startups: NIH, NSF, SBIR/STTR, and Non-Dilutive Funding
A practical guide to grants for biotech startups, including NIH SBIR/STTR, NSF, translational funding, evidence, regulatory readiness, and budgets.
Start hereCommercialization Plan for SBIR and Deeptech Grants
Learn how to write a commercialization plan for SBIR and deeptech grants, with market, IP, regulatory, customer, milestone, and funding sections.
Submit & reportSAM.gov Registration and UEI Guide for Federal Grant Applicants
Learn how SAM.gov registration, UEI numbers, Grants.gov accounts, organization profiles, workspace roles, and renewal timing fit together.
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NHLBI SBIR/STTR — Standard
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Supports small businesses advancing heart, lung, blood, and sleep-related technologies through NHLBI.
DoD SBIR/STTR
🇺🇸DoD · United States
Supports small business and non-traditional teams across defense components in a shared topic flow.
NSF SBIR/STTR Fast-Track Pilot
🇺🇸NSF · United States
Supports United States deep-tech startups through a combined early and continuation development route.
NCI SBIR/STTR Omnibus (Next Receipt 5)
🇺🇸NCI · United States
Supports small businesses developing cancer technologies through national NIH collaboration pathways.
NSF SBIR Phase II
🇺🇸NSF · United States
Funds United States deep-tech startups extending proven early projects into substantial technology development.
NSF STTR Phase II
🇺🇸NSF · United States
Funds United States deep-tech projects that continue with nonprofit research partners after successful initial feasibility work.