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FDA Rare Neurodegenerative Disease Grants Program

Clinical Trials Addressing Unmet Needs of Rare Neurodegenerative Diseases

Funds clinical testing research for rare neurodegenerative disorders and therapeutic development.

Between cyclesFDA Office of Orphan Products DevelopmentUnited States

The FDA Rare Neurodegenerative Disease Grants Program was established by the ACT for ALS Act of 2021 and has been active since 2022. Administered by the FDA Office of Orphan Products Development, the program funds clinical trials of interventions intended to prevent, diagnose, mitigate, treat, or cure amyotrophic lateral sclerosis (ALS) and other rare neurodegenerative diseases in both adults and …

Clinical trials of interventions to prevent, diagnose, mitigate, treat, or cure ALS and other rare neurodegenerative diseases in adults and children, funded under the ACT for ALS Act of 2021.

CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.Annual
Next deadlineiThe next date applications are due. Rolling means you can apply any time.—
Decision timeiTypical time from the deadline to the funder's decision.—
Project durationiHow long the funded work is expected to run.—
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.0%
Funding pooliThe total budget available across all awards in this round.—

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Last verified: 22 Jul 2026Source: www.fda.gov