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Grand Challenges

Grand Challenges — Micronutrient Absorption Barriers in Fortified Foods

Funds global teams researching novel approaches to overcome infection, inflammation, and microbiome-related barriers that reduce the effectiveness of food fortification programs.

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This Grand Challenge is run by the Gates Foundation under its Grand Challenges program. It funds research that identifies and overcomes physiological barriers — chronic inflammation, gut microbiome disruption, environmental enteric dysfunction — that prevent food fortification programs from delivering micronutrients effectively in low-resource settings. Awards are up to $250,000 per project with a…

Biomarkers for impaired micronutrient utilization, optimized fortificant formulations for inflammatory states, gut health restoration strategies, microbiome-modulating approaches, anti-inflammatory adjuncts, integrated interventions combining infection control and micronutrient delivery. Focus on iron, zinc, and fat-soluble vitamins.

CycleiHow often this grant runs - e.g. annually, on a rolling basis, or a one-off call.No fixed schedule
Next deadlineiThe next date applications are due. Rolling means you can apply any time.-
Decision timeiTypical time from the deadline to the funder's decision.17 weeks
Project durationiHow long the funded work is expected to run.18 months
Award typeiThe form of funding - grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.0%
Funding pooliThe total budget available across all awards in this round.-

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Grand Challenges — Breakthrough Innovations to Reduce the Cost of Severe Acute Malnutrition Treatment

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Grand Challenges — Cost-Reducing Innovations for Ready-to-Use Therapeutic Food

Gates Foundation · United States

Funds global teams developing innovations in protein, lipids, packaging, and manufacturing that reduce the ex-factory unit cost of ready-to-use therapeutic food by at least 30%.

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Grand Challenges — Placental and Gut Inflammation Interventions for Fetal Growth

Gates Foundation · United States

Funds global teams developing drug, biologic, dietary, or microbiome-based interventions that target placental and gut inflammatory pathways to improve fetal growth outcomes in low-income countries.

BiotechMedtech+1
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Grand Challenges — Ultralow-Cost Diagnostics and Screening for Low-Income Countries

Gates Foundation · United States

Funds global teams developing diagnostic devices and screening tools that cost approximately $1 per test or near-zero incremental cost per person screened for deployment in low-income countries.

BiotechMedtech+6
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