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NCATS SBIR/STTR Small Business Programs

NCATS SBIR Phase I

Supports small businesses testing translational science tools and technologies through early feasibility and commercialization groundwork.

OpenNational Center for Advancing Translational SciencesUnited States
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About

The National Center for Advancing Translational Sciences (NCATS), a component of the National Institutes of Health, administers SBIR Phase I grants (R43) to fund small US businesses seeking to establish the technical merit and feasibility of translational science innovations. NCATS focuses on four priority topic areas: preclinical drug discovery and development, biomedical and clinical and health …

What this grant funds

Feasibility research for small businesses in NCATS priority areas: preclinical drug discovery, biomedical and health research informatics, clinical and implementation research, and rare disease.

Key facts
CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.Multiple per year
Next deadlineiThe next date applications are due. Rolling means you can apply any time.—
Decision timeiTypical time from the deadline to the funder's decision.—
Project durationiHow long the funded work is expected to run.—
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.0%
Funding pooliThe total budget available across all awards in this round.—
Funding analytics

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Industries

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Eligibility criteria

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Application process

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Timeline

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Last verified: 22 Jul 2026Source: ncats.nih.gov