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NCATS SBIR/STTR Small Business Programs

NCATS SBIR Phase II

Backs small businesses scaling proven translational findings into applied solutions and early market readiness.

OpenNational Center for Advancing Translational SciencesUnited States

The National Center for Advancing Translational Sciences (NCATS) administers SBIR Phase II grants (R44) to support expanded research, development, and early commercialization activities for small US businesses that have demonstrated feasibility in a Phase I award. NCATS's four priority topic areas — preclinical drug discovery and development, biomedical and health research informatics, clinical an…

Expanded R&D and commercialization for small businesses in preclinical drug discovery, biomedical informatics, clinical and dissemination research, and rare disease applications.

CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.Multiple per year
Next deadlineiThe next date applications are due. Rolling means you can apply any time.—
Decision timeiTypical time from the deadline to the funder's decision.—
Project durationiHow long the funded work is expected to run.—
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.0%
Funding pooliThe total budget available across all awards in this round.—

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Last verified: 22 Jul 2026Source: ncats.nih.gov