NCATS STTR Phase I
Funds U.S. small businesses and their nonprofit research partners to conduct feasibility studies on translational science innovations toward commercialization.
NCATS STTR Phase I is a six-month feasibility grant for U.S. small businesses working in partnership with a nonprofit research institution (university, hospital, or federal lab). It runs under the NIH SBIR/STTR Omnibus Solicitation — the same grant vehicle used by all NIH institutes — but NCATS selects applicants whose work fits its specific translational science priorities. Awards are normally $3…
Any biomedical or behavioral research area within NCATS's translational science mission: drug discovery, diagnostics, medical devices, informatics, and platform technologies that advance translation of basic research findings to clinical or commercial use. NCATS-specific priorities include rare diseases, toxicology, clinical trial innovation, and translational informatics.
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Guides for this application
All guides →SBIR/STTR Grants for Deeptech Startups
A practical guide to SBIR and STTR grants for deeptech startups, including agency fit, Phase I and II logic, eligibility, budgets, and review criteria.
DocumentsNIH Biosketch Guide: Format, SciENcv Steps, and Examples
Learn what an NIH biosketch is, how the format works, what to prepare for SciENcv, and how startup teams should avoid common biosketch mistakes.
Write proposalHow to Write a Specific Aims Page
Learn how to write a specific aims page for NIH, SBIR-adjacent, and translational R&D grants, with structure, reviewer logic, examples, and common mistakes.
Where to applyGrants for Biotech Startups: NIH, NSF, SBIR/STTR, and Non-Dilutive Funding
A practical guide to grants for biotech startups, including NIH SBIR/STTR, NSF, translational funding, evidence, regulatory readiness, and budgets.
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