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NCATS STTR Phase I

NCATS STTR Phase II

Funds U.S. small businesses and their nonprofit research partners to continue and expand translational R&D begun in STTR Phase I toward a commercial product.

OpenNational Center for Advancing Translational SciencesUnited States

NCATS STTR Phase II is the continuation grant that follows a successful STTR Phase I award. It funds the expansion of the R&D work initiated in Phase I, with the goal of producing a commercial product, process, or service. Awards are normally $2,095,748 in total costs over a two-year project period. Applications may exceed this amount with prior approval from the NCATS Grants Management Officer.

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Continuation of research and development from STTR Phase I, within NCATS's translational science mission: drug discovery, diagnostics, medical devices, informatics, and platform technologies. NCATS-specific priorities include rare diseases, toxicology, clinical trial innovation, and translational informatics. Phase II must continue work from a prior Phase I — it is not an entry-level grant.

CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.Multiple per year
Next deadlineiThe next date applications are due. Rolling means you can apply any time.5 Sept 2026
Decision timeiTypical time from the deadline to the funder's decision.30 weeks
Project durationiHow long the funded work is expected to run.24 months
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.0%
Funding pooliThe total budget available across all awards in this round.—

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Last verified: 22 Jul 2026Source: ncats.nih.gov