NEI SBIR Phase II — R&D
Supports United States. small businesses scaling vision concepts into full development pathways.
The NIH National Eye Institute (NEI) SBIR Phase II program (R44) funds U.S. small businesses to execute full research and development projects in vision-related technology, building on successful Phase I feasibility results. NEI administers SBIR through its three extramural program divisions covering Retina/Glaucoma/Low Vision, Anterior Segment (Cornea, Lens, Dry Eye), and Strabismus/Amblyopia/Vis…
Vision-related R&D: retina, glaucoma, cornea, lens, low vision, amblyopia/strabismus, and related ocular/visual technologies with commercial potential.
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Guides for this application
All guides →SBIR/STTR Grants for Deeptech Startups
A practical guide to SBIR and STTR grants for deeptech startups, including agency fit, Phase I and II logic, eligibility, budgets, and review criteria.
DocumentsNIH Biosketch Guide: Format, SciENcv Steps, and Examples
Learn what an NIH biosketch is, how the format works, what to prepare for SciENcv, and how startup teams should avoid common biosketch mistakes.
Write proposalHow to Write a Specific Aims Page
Learn how to write a specific aims page for NIH, SBIR-adjacent, and translational R&D grants, with structure, reviewer logic, examples, and common mistakes.
Where to applyGrants for Biotech Startups: NIH, NSF, SBIR/STTR, and Non-Dilutive Funding
A practical guide to grants for biotech startups, including NIH SBIR/STTR, NSF, translational funding, evidence, regulatory readiness, and budgets.
More from NEI
All grants from this funder →NEI SBIR Phase I — Feasibility
🇺🇸NEI · United States
Supports United States. small businesses testing vision concepts through feasibility-focused grants.
NEI STTR Phase I — Feasibility
🇺🇸NEI · United States
Funds small business and research-partner teams on feasibility vision tools for future commercialization.
NEI STTR Phase II — R&D
🇺🇸NEI · United States
Funds collaborative small-business partnerships to mature vision innovation into market-ready healthcare technologies.
NEI R01 Research Project Grant
🇺🇸NEI · United States
Funds investigator-led basic and clinical vision science at research institutions across the United States.
NIH Data Sharing Index (S-index) Challenge
🇺🇸NEI · United States
Pays up to $500,000 from a $1 million pool for a new data-sharing measurement tool.
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