NIMHD SBIR Phase IIB Strategic Breakthrough Award
Funds prior NIH SBIR and STTR Phase II small businesses bridging later-stage R&D to commercialization.
The NIMHD SBIR Phase IIB Strategic Breakthrough Award is the institute-relevant route into NIH PA-27-101, an R44 follow-on opportunity for small businesses with prior NIH SBIR or STTR Phase II funding. Simpler.Grants.gov lists the opportunity as posted May 28, 2026, with closing on April 5, 2029.
This is not a duplicate of the base SBIR parent grant. Phase IIB bridges the funding gap between the …
Later-stage research and development after an NIH SBIR or STTR Phase II award, focused on moving health-related technologies toward commercialization.
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Guides for this application
All guides →SBIR/STTR Grants for Deeptech Startups
A practical guide to SBIR and STTR grants for deeptech startups, including agency fit, Phase I and II logic, eligibility, budgets, and review criteria.
DocumentsNIH Biosketch Guide: Format, SciENcv Steps, and Examples
Learn what an NIH biosketch is, how the format works, what to prepare for SciENcv, and how startup teams should avoid common biosketch mistakes.
Write proposalHow to Write a Specific Aims Page
Learn how to write a specific aims page for NIH, SBIR-adjacent, and translational R&D grants, with structure, reviewer logic, examples, and common mistakes.
Where to applyGrants for Biotech Startups: NIH, NSF, SBIR/STTR, and Non-Dilutive Funding
A practical guide to grants for biotech startups, including NIH SBIR/STTR, NSF, translational funding, evidence, regulatory readiness, and budgets.
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