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NIH SBIR / STTR — Small Business Innovation Research and Small Business Technology Transfer

NIH SBIR Phase II

Supports United States biomedical small businesses advancing successful feasibility work into scale-up development.

NIH SBIR Phase II awards provide non-dilutive grant funding for small businesses to continue and scale the R&D work initiated under a Phase I award, with the goal of advancing innovations toward commercialization. The budget cap for Phase II is $2,153,927 for a project period of one to three years. Phase II applicants must have completed a Phase I award (or qualify for Direct-to-Phase II if feasib

Continuation and scale-up of Phase I biomedical feasibility R&D toward commercialization, across all 24 participating NIH Institutes and Centers.

CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.Multiple per year
Next deadlineiThe next date applications are due. Rolling means you can apply any time.5 Sept 2026
Decision timeiTypical time from the deadline to the funder's decision.
Project durationiHow long the funded work is expected to run.12–36 months
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.0%
Funding pooliThe total budget available across all awards in this round.

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Last verified: 24 Jul 2026Source: seed.nih.gov