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  4. /Lewis & Clark Ventures
L&

Lewis & Clark Ventures

GeneralistSt. Louis, United StatesActiveWebsiteLinkedIn
Stage FocusSeed, Series A
GeographyUS
TypeVC
Last Activity2025
Industry Focus
Industries
AI
Technical BenchLimited
Investor TypeGeneralist
ExposureMinimal DeepTech Investments
Bio

Lewis & Clark Ventures is an early-stage venture capital firm based in St. Louis, Missouri, founded by former startup founders and operators. It invests in late-seed through Series A B2B software companies, typically writing $2M-$3M initial checks and preferring to lead rounds. The firm explicitly targets founders in geographies overlooked by coastal venture funds, describing its focus as 'between...

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