CFF Clinical Pilot and Feasibility Award

The CFF Clinical Pilot and Feasibility Award funds early clinical work in cystic fibrosis by supporting preliminary data collection for larger trials. It sits in the Cystic Fibrosis Foundation's clinical research portfolio and is aimed at proof-of-concept studies rather than full trial support. Awards run from $80,000 to $150,000 a year for two years, with 12% indirect costs. The program has two cycles each year: a fall round with letters of inquiry due in April and full applications due in August, and a spring round with letters of inquiry due in October and full applications due in February. An LOI is required before full submission, applications are reviewed by the Clinical Research Committee, and the award is limited to U.S. universities and research organizations. The strongest applications show a clear clinical question, enough feasibility to justify the proposed study, and a credible path to a larger trial. The award is most useful when a team can generate the preliminary data that unlocks the next clinical step.

Each grant below is a distinct funding opportunity with its own eligibility, scope, and deliverables.