CFF Mission Ventures Industry Investment

CFF Mission Ventures Industry Investment is the Cystic Fibrosis Foundation's venture-philanthropy arm in the United States. It backs pharma and biotech companies developing cystic fibrosis treatments, and it does so with the same logic as an investor rather than a traditional grantmaker. The record frames it as a company-facing route for programs that move beyond academic discovery and into development. Investments are usually structured as milestone-based venture-philanthropy contracts with royalty or equity stakes, and the typical deal size runs from $5 million to $25 million or more. The route is rolling, limited to for-profit companies, and designed for teams working at the intersection of therapeutics, clinical development, and commercialization. Alongside capital, CFF can add scientific and strategic support, including patient samples, introductions to key opinion leaders, and help with clinical trial design. That combination matters because CFF is not only trying to back a broad disease area; it is trying to move specific CF treatments through development with added scientific leverage. Mission Ventures is the better fit when a company has a plausible treatment program, a clear development plan, and enough data to justify a negotiated investment relationship.

Each grant below is a distinct funding opportunity with its own eligibility, scope, and deliverables.