CFF Screening Improvement Program (SIP)

The CFF Screening Improvement Program (SIP) sits inside the Cystic Fibrosis Foundation's care-enhancement track in the United States. It supports quality improvement work on newborn CF screening, early diagnosis, and follow-up rather than laboratory research, and the award is fixed at $75,000 a year for two years. Because the program is built around service delivery, the strongest applicants are institutions that can change screening pathways and track outcomes in real clinical systems. The funding is a grant with 12% indirect costs, a July annual deadline, and review by an ad hoc committee. Eligibility points to U.S. universities, nonprofit organizations, and research organizations, while for-profit applicants and individuals are not in scope. The program's subject matter is narrow and practical: better screening pathways, faster diagnosis, and tighter follow-up after a positive newborn screen. SIP fits teams that can show a defined process problem, a measurable intervention, and a way to sustain the change after the award ends. CFF uses it as a care-improvement mechanism, so proposals land best when they are operationally grounded, tied to newborn screening workflows, and able to demonstrate improvement in time to diagnosis or follow-up completion.

Each grant below is a distinct funding opportunity with its own eligibility, scope, and deliverables.