Clinical and Translational Science Awards (CTSA)
Supports academic medical centres through cooperative agreements to strengthen translational science infrastructure.
The Clinical and Translational Science Awards program is NCATS's largest hub network, built to help US academic medical centers move discoveries into patient care. It funds more than 60 institutions through cooperative agreements and sits at the center of NCATS's institutional translational-science strategy. The primary mechanism is UM1, with older hubs and some sub-components still using U54. Companion KL2 and TL1 awards support mentored career development and training, and hub funding is commonly in the $5 million to $10 million a year range; a May 2026 award sent $50 million to UMass for its Center for Clinical and Translational Science. Eligibility is limited to US academic medical institutions with a hub-based consortium structure. The program is built for institutions that can show scale, partnership, and operational maturity. Strong applicants usually have a broad translational science agenda, a connected campus or regional network, and the ability to run shared clinical research infrastructure well enough to improve study quality, speed, and training across the system.
No upcoming rounds verified. Cadence: Rolling.