NCI Bioengineering Research Grants (BRG)

NCI Bioengineering Research Grants (BRG) is an NIH/NCI R01 program run by the National Cancer Institute, with NICHD and NEI as participating institutes. It supports multidisciplinary bioengineering projects that address cancer biology problems, and the current PAR-27-072 stays open through July 2029. It is unusual at NCI because foreign organizations can apply directly. The award ceiling is $500,000 in direct costs per year. Eligible applicants include higher education institutions, nonprofits, small businesses, for-profits, and state, local, and tribal governments. The program backs teams that integrate life and physical sciences to translate tools, methods, and techniques, including work on cancer diagnostics and broader cancer bioengineering. BRG fits groups with a defined biomedical problem and a multidisciplinary plan that can support design-directed, developmental, discovery-driven, or hypothesis-driven work. Because it is a standing PAR with a long closing date, applicants can plan around a multi-year window rather than a single annual deadline. That also gives consortia time to assemble the right mix of engineering, biology, and clinical expertise.

Each grant below is a distinct funding opportunity with its own eligibility, scope, and deliverables.