NIEHS SBIR / STTR
Supports United States small businesses creating environmental health technologies through commercialization-focused grants.
NIEHS participates in the NIH-wide SBIR/STTR program to support U.S. small businesses developing environmental health technologies. The program sits under the National Institute of Environmental Health Sciences and gives firms a route into federal R&D around exposure, monitoring, remediation, diagnostics, and related tools. It is a grant program open to U.S. for-profit companies with fewer than 500 employees. Phase I uses R43/R41 mechanisms and provides roughly $300,000 over 6 to 12 months for feasibility work; Phase II uses R44/R42 and provides up to $2,000,000 over 2 years for development. STTR requires a formal research-institution partner, and the record marks a disadvantage bonus for eligible applicants. The strongest submissions show a specific technical problem, a credible commercial path, and a clear environmental health use case. Because the program follows NIH-wide SBIR rules and appears multiple times per year, founders usually need a concise development plan and a team structure that matches the phase they are seeking.
Each grant below is a distinct funding opportunity with its own eligibility, scope, and deliverables.