Lupus Research Alliance
Funds lupus-focused research in the United States through nonprofit support for high-impact investigator collaboration.
The Lupus Research Alliance is a New York City-based 501(c)(3) foundation focused on discovering and developing lupus diagnostics and curative treatments. It says that 100% of donations go to research programs, and its track record now exceeds $284 million awarded across 675+ grants to academic and medical investigators worldwide.
Its portfolio spans the full continuum from foundational science to clinical translation. Current programs include the $3 million Global Team Science Award, the $750,000 Mechanistic Clinical Award, the up-to-$450,000 Translational Bridge Award, the Targeted Research Program on Engineered Cell Therapies for Lupus, the $300,000 Lupus Innovation Award, the LRA-Genentech immune-resetting award, the LRA/RRF investigator and scientist development awards, and the Empowering Lupus Research supplement and Lupus Insight Prize.
The alliance uses those awards to push molecular understanding, stratification tools, and immune-resetting therapies, and its 2024-2028 roadmap keeps the work centered on lupus heterogeneity and better clinical translation. Clinical activity runs through Lupus Therapeutics, while partnerships such as Breakthrough T1D and the National Multiple Sclerosis Society expand its collaboration on shared autoimmune mechanisms.