European Commission logo
Horizon Europe Cluster 4 — Twin (Green+Digital) Transition for Industry

Safer Alternatives to Industrial Substances

Funds industrial substitutes for substances of concern, covering design, production, manufacturing integration and market uptake.

ClosedEuropean CommissionEU

Substances of concern create health, environmental, regulatory and supply-chain risks across European industry. This topic supports replacements that retain the performance manufacturers need while being safer and more sustainable throughout their lifecycle.

Projects must develop alternatives to substances of concern as defined by the Ecodesign for Sustainable Products Regulation. The work should

Projects must develop alternatives to substances of concern as defined by the Ecodesign for Sustainable Products Regulation. The work should cover redesign, development, production processes and integration into manufactured products, using the safe-and-sustainable-by-design framework to compare hazards, impacts and performance.

CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.One-off
Next deadlineiThe next date applications are due. Rolling means you can apply any time.
Decision timeiTypical time from the deadline to the funder's decision.22 weeks
Project durationiHow long the funded work is expected to run.
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.30%
Funding pooliThe total budget available across all awards in this round.€38M

Sign up free to see the funding breakdown

Sign up free to see the industries in scope

Sign up free to see the full eligibility

Sign up free to see how to apply

Sign up free to see what you submit

Sign up free to see how they score you

Sign up free to see the timeline

Sign up free to see where teams trip up

Last verified: 25 Aug 2026Funder reference: HORIZON-CL4-2026-02-MAT-PROD-21-TWO-STAGESource: ec.europa.eu