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Horizon Europe Cluster 1 — Health (HLTH)

Clinical trials for advancing innovative interventions for neurodegenerative diseases

Funds early clinical trials of safer, more effective interventions for non-rare neurodegenerative diseases.

ScheduledEuropean CommissionEU

Stage 1 must establish the scientific rationale, clinical promise and expected impact in a blind outline. Stage 2 should provide adequately powered, representative clinical trials, insight into mechanisms of action, and a robust pathway for long-term efficacy, implementation and uptake. Proposals may use imaging, biomarkers, omics, registries, biobanks, AI or wearable technologies, while applying

This two-stage Research and Innovation Action supports rigorous early-stage clinical trials of innovative interventions for non-rare neurodegenerative diseases. Projects should combine an active substance with a complementary multidisciplinary approach, such as rehabilitation, cognitive training or lifestyle change, to improve quality of life and reduce disease burden.

CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.One-off
Next deadlineiThe next date applications are due. Rolling means you can apply any time.13 Apr 2027
Decision timeiTypical time from the deadline to the funder's decision.22 weeks
Project durationiHow long the funded work is expected to run.
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.0%
Funding pooliThe total budget available across all awards in this round.€39.3M

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Last verified: 25 Aug 2026Funder reference: HORIZON-HLTH-2027-02-DISEASE-14-TWO-STAGESource: ec.europa.eu