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Challenge Works

Longitude Prize on ALS

Funds AI-driven ALS drug-discovery teams through four stages worth up to £7.5 million total.

ClosedChallenge WorksUnited Kingdom

Teams progress through four stages over more than five years: Discovery (20 teams receive £100,000 to identify therapeutic targets), Prioritise (10 of those teams receive a further £200,000 to build the evidence base), Validate (5 teams receive £500,000 for wet-lab validation), and a final Winner stage where one team receives £1,000,000. An expert panel assesses and judges teams between each stage

The prize backs teams that apply artificial-intelligence methods to speed up drug discovery for ALS (amyotrophic lateral sclerosis), the most common subtype of motor neurone disease. It funds work that finds and confirms strong new drug targets for the condition.

CycleiHow often this grant runs - e.g. annually, on a rolling basis, or a one-off call.No fixed schedule
Next deadlineiThe next date applications are due. Rolling means you can apply any time.-
Decision timeiTypical time from the deadline to the funder's decision.-
Project durationiHow long the funded work is expected to run.-
Award typeiThe form of funding - grant, equity, loan, tax credit, etc.Prize
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.-
Funding pooliThe total budget available across all awards in this round.£7.5M

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