RFA: Establishing Immune Tolerance in Islet Cell Replacement Therapy
Funds type 1 diabetes research to improve immune tolerance pathways for safer islet-based replacement approaches.
Breakthrough T1D — the former JDRF, rebranded in June 2024 — issued this FY26 Request for Applications to solicit focused research on one of the primary barriers to widespread islet cell replacement therapy for type 1 diabetes: the dependence on chronic systemic immunosuppression. The RFA titled "Establishing Immune Tolerance in Islet Cell Replacement Therapy" targets investigators developing immu…
Immunological strategies to establish immune tolerance in islet cell replacement therapy, with the aim of reducing or eliminating dependence on chronic systemic immunosuppression.
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