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Research Funding Opportunities (Topic RFAs)

RFA: Establishing Immune Tolerance in Islet Cell Replacement Therapy

Funds type 1 diabetes research to improve immune tolerance pathways for safer islet-based replacement approaches.

ClosedBreakthrough T1DUnited States
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About

Breakthrough T1D — the former JDRF, rebranded in June 2024 — issued this FY26 Request for Applications to solicit focused research on one of the primary barriers to widespread islet cell replacement therapy for type 1 diabetes: the dependence on chronic systemic immunosuppression. The RFA titled "Establishing Immune Tolerance in Islet Cell Replacement Therapy" targets investigators developing immu…

What this grant funds

Immunological strategies to establish immune tolerance in islet cell replacement therapy, with the aim of reducing or eliminating dependence on chronic systemic immunosuppression.

Key facts
CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.One-off
Next deadlineiThe next date applications are due. Rolling means you can apply any time.—
Decision timeiTypical time from the deadline to the funder's decision.—
Project durationiHow long the funded work is expected to run.—
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.0%
Funding pooliThe total budget available across all awards in this round.—
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Last verified: 22 Jul 2026Source: www.breakthrought1d.org