Peer Reviewed Medical Research Program (PRMRP)

PRMRP — Peer Reviewed Medical Research Program

Backs research teams and institutions for PRMRP Peer Reviewed Medical Research in biotechnology, medical technology, and artificial intelligence.

The Peer Reviewed Medical Research Program (PRMRP) is a congressionally directed programme administered by the Congressionally Directed Medical Research Programs (CDMRP) office within the U.S. Army Medical Research and Development Command (USAMRDC). PRMRP is the broadest medical research programme in the CDMRP portfolio: for FY2026, Congress appropriated $370 million across 52 distinct topic areas, with the programme announcement released on May 8, 2026. Topics span a wide range of military-relevant medical conditions including trauma, neurological disease, infectious disease, and general biomedical science priorities identified through the congressional appropriations process.

FY2026 PRMRP offers seven award mechanisms calibrated to different stages of the research pipeline. Discovery Award and Research Advancement Award — both targeting early-stage and translational science — have a Letter of Intent deadline of July 16, 2026 and a full-application deadline of July 30, 2026. The Clinical Trial Award and Platform Clinical Translation Award — supporting clinical research infrastructure and interventional studies — have a pre-application deadline of July 23, 2026 and a full-application deadline of September 22, 2026. The Impact Award, Lifestyle and Applied Health Research Award, and Technology/Therapeutic Development Award have an LOI/pre-app deadline of July 23, 2026 and a full-application deadline of August 6, 2026. Award ceilings vary by mechanism and are published in each mechanism's programme announcement PDF. Universities, non-profit research organisations, for-profit companies, and foreign entities are all eligible; individuals may not apply directly. SAM.gov UEI registration is required.

All PRMRP submissions follow the CDMRP two-step process: pre-application or Letter of Intent through the eBRAP portal, followed by an invitation to submit a full proposal via Grants.gov. Applicants must match their submission to one of the 52 designated topic areas and select the mechanism appropriate to their research stage. Dual peer-review (scientific and programmatic) applies to all mechanisms. Proposals addressing military and veteran populations, incorporating sex as a biological variable, and including consumer advocates in study design have historically scored well in PRMRP programmatic review.