CRF Research Grant
Administers research teams and institutions for CRF Research Grant in biotechnology, medical technology, and synthetic biology.
Eligibility · United States, Canada, Germany, Australia, United Kingdom, Italy +7 more
The Cystinosis Research Foundation (CRF) Research Grant is a competitive award program supporting bench, clinical, and translational research directed at improving treatments or achieving a cure for cystinosis, a rare lysosomal storage disorder caused by mutations in the CTNS gene. CRF has funded 255 awards across 13 countries and has committed more than $73 million to cystinosis research since 2003. Topics funded include kidney disease mechanisms, corneal involvement, skeletal myopathy, neurological complications, and gene and stem cell therapy approaches. Academic laboratories, research institutions, and nonprofit research organizations are eligible; for-profit companies are not.
Award sizes range from approximately $75,000 for focused discovery studies to $400,000 for larger collaborative projects, with a typical grant around $150,000. Projects run one to two years. The total annual pool is approximately $2 million shared across research grants and postdoctoral fellowships. Scientific merit is evaluated against NIH-scale standards. Recent 2025 awards went to teams at Harvard, McGill, Scripps Research, University of Zurich, and Bambino Gesù Children's Hospital in Italy, confirming broad international eligibility. Grant payments are linked to progress report submission; delays in reporting can hold disbursements.
The Spring 2026 call closed before this cycle. The Fall 2026 call opens August 1, 2026, when guidelines are published. Applicants should contact nstack@cystinosisresearch.org to be added to the announcement list. Applications require a Grant Proposal Cover Sheet along with scientific and budget materials per published guidelines. A final report and one-page Budget Report of Receipts and Expenditures are required at project close. Indirect cost policy is not published; teams should contact CRF before building budgets. The fall cycle is the next available entry point for new applications in 2026.
Funds bench, clinical, and translational research into cystinosis and its complications — including kidney disease, myopathy, neurological conditions, corneal involvement, and gene or stem cell therapy approaches — with awards typically ranging from $75,000 to $400,000 over one to two years.
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