NIH HEAL Initiative — Open NOFOs
Supports opioid, pain, and substance use disorder research in the NIH HEAL portfolio.
The NIH HEAL (Helping to End Addiction Long-term) Initiative is a trans-NIH research portfolio addressing the national opioid overdose and pain management crisis, administered across multiple NIH Institutes and Centers rather than by a single IC. As of May 2026, HEAL has more than 20 active NOFOs with deadlines spanning July 2026 through August 2028, plus approximately 10 forecasted opportunities …
Opioid overdose prevention, non-addictive pain management, substance use disorder treatment, analgesic drug discovery, and health services research across the NIH HEAL trans-agency portfolio.
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