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NIH IGNITE Program (NINDS) — Innovation Grants to Nurture Initial Translational Efforts

NIH IGNITE Program — R61/R33 Phased Neurotherapeutic Grants

Supports early neurotherapeutic translation through milestone-based translational funding.

OpenNational Institutes of HealthUnited States

The NINDS IGNITE program — Innovation Grants to Nurture Initial Translational Efforts — provides milestone-gated, phased R61/R33 funding for early-stage neurotherapeutic development, serving as the primary feeder into the later-stage NIH Blueprint Neurotherapeutics Network for small molecules (BPN) and BPN-Biologics. Three active NOFOs cover distinct development stages: PAR-25-059 (assay developme…

Early-stage neurotherapeutic development including assay development, model system validation, and agent characterization for small-molecule and biologic candidates targeting neurological diseases.

CycleiHow often this grant runs - e.g. annually, on a rolling basis, or a one-off call.Multiple per year
Next deadlineiThe next date applications are due. Rolling means you can apply any time.-
Decision timeiTypical time from the deadline to the funder's decision.-
Project durationiHow long the funded work is expected to run.36 months
Award typeiThe form of funding - grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.0%
Funding pooliThe total budget available across all awards in this round.-

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