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NIH IGNITE Program (NINDS) — Innovation Grants to Nurture Initial Translational Efforts

NIH IGNITE Program — R61/R33 Phased Neurotherapeutic Grants

Supports early neurotherapeutic translation through milestone-based translational funding.

Between cyclesNational Institutes of HealthUnited States

The NINDS IGNITE program — Innovation Grants to Nurture Initial Translational Efforts — provides milestone-gated, phased R61/R33 funding for early-stage neurotherapeutic development, serving as the primary feeder into the later-stage NIH Blueprint Neurotherapeutics Network for small molecules (BPN) and BPN-Biologics. Three active NOFOs cover distinct development stages: PAR-25-059 (assay developme

Early-stage neurotherapeutic development including assay development, model system validation, and agent characterization for small-molecule and biologic candidates targeting neurological diseases.

CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.Multiple per year
Next deadlineiThe next date applications are due. Rolling means you can apply any time.
Decision timeiTypical time from the deadline to the funder's decision.
Project durationiHow long the funded work is expected to run.36 months
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.0%
Funding pooliThe total budget available across all awards in this round.

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Last verified: 30 Jul 2026Source: www.ninds.nih.gov