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NHLBI Catalyze Program

NHLBI Catalyze — Reissue

Supports NHLBI translational pathways toward first-in-human feasibility testing.

Between cyclesNational Heart, Lung, and Blood InstituteUnited States

NHLBI Catalyze is a translational research program designed to help basic science discoveries in heart, lung, blood, and sleep (HLBS) biology cross the threshold into viable diagnostic and therapeutic candidates cleared for first-in-human testing. The program provides R61/R33 phased awards: the R61 phase functions as a milestone-gated feasibility period, and the R33 phase funds execution after mil

Translational research facilitating HLBS basic science discoveries into diagnostic and therapeutic candidates cleared for first-in-human testing, covering enabling platforms, small molecules, biologics, and devices.

CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.Annual
Next deadlineiThe next date applications are due. Rolling means you can apply any time.
Decision timeiTypical time from the deadline to the funder's decision.
Project durationiHow long the funded work is expected to run.
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.0%
Funding pooliThe total budget available across all awards in this round.

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Last verified: 24 Jul 2026Source: www.nhlbi.nih.gov