
National Heart, Lung, and Blood Institute
Funds NHLBI, a National Institutes of Health institute focused on heart, lung, blood, and sleep condition progress.
National Heart, Lung, and Blood Institute (NHLBI) is one of NIH's 27 Institutes and Centers and funds work on heart, lung, blood, and sleep disorders. It sits within NIH and HHS and supports both investigator-initiated research and translation into clinical and commercial use.
The institute uses NIH-wide parent mechanisms alongside NHLBI-specific solicitations, including SBIR and STTR, Catalyze, loan repayment, and small-grant routes for K award recipients. Award sizes in this portfolio run up to $2.4 million for small business SBIR, $2.1 million for the combined SBIR and STTR route, $3.5 million for Phase IIB Bridge awards, and $50,000 for the loan repayment program. Those figures make the translational path unusually clear.
NHLBI is a strong fit for teams building cardiovascular, pulmonary, blood, or sleep-related technologies that need a translational path. Applicants do best when they can show clinical relevance and a clear step from early development into validation, since the institute mixes standard parent calls with HL-prefix opportunities and targeted commercialization support.