NINR Areas of Emphasis R01

NINR Areas of Emphasis R01

Supports nursing research projects in the United States across five priority areas.

The National Institute of Nursing Research (NINR) is an NIH institute established by Congress in 1986 that leads nursing science to address pressing health challenges and inform clinical practice and policy. The NINR Areas of Emphasis R01 (re-issuance of PAR-22-230, announced via NOT-NR-25-006 on November 21, 2024) funds research grants aligned with NINR's 2022–2026 Strategic Plan across five priority areas: Optimizing Health for All, Addressing the Conditions of Daily Life, Addressing the Distribution of Health, Preventing and Managing Disease, and Advancing Systems to Optimize Care. Clinical trials are optional under this announcement, and funding is catalogued under CFDA Assistance Listing 93.361 (Nursing Research).

Application budgets carry no ceiling — they must reflect actual project needs and be fully justified. The first application due date under the re-issued NOFO (published January 8, 2025) was February 5, 2025, with the earliest possible award and project start date of December 1, 2025. Eligible applicants include U.S. higher education institutions (public and private), 501(c)(3) nonprofits, small businesses, for-profit organizations, state and local governments, tribal governments, and U.S. territories. Federal agencies are explicitly ineligible. Applications are accepted on standard NIH review cycles year-round.

Competitive R01 applications to NINR must frame the research problem squarely within at least one of the five strategic priority areas and articulate how findings will advance nursing science, practice, or policy. Reviewers apply NIH's standard five-criterion scoring rubric (Significance, Investigators, Innovation, Approach, Environment). Program contact is David L. Tilley, MPH, MS, CPH (david.tilley@nih.gov). Applicants with existing NINR relationships or preliminary data addressing health equity, symptom burden, self-management, or care systems are well positioned.