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Complement Animal Research In Experimentation (Complement-ARIE)

Complement-ARIE — Open Funding (Seed)

Supports development of human-based new approach methodologies replacing animal models in relevant research.

OpenNIH Common FundUnited States
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About

Complement-ARIE (Complement Animal Research In Experimentation) is an NIH Common Fund program approved by the NIH Council of Councils on January 25, 2024. Its mission is to accelerate the development, standardization, validation, and deployment of human-based New Approach Methodologies (NAMs) — laboratory and computational approaches intended to more accurately model human biology and to complemen…

What this grant funds

Funds development, standardization, validation, and deployment of human-based New Approach Methodologies (NAMs) intended to complement or replace animal models in biomedical and drug research.

Key facts
CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.Rolling
Next deadlineiThe next date applications are due. Rolling means you can apply any time.Rolling
Decision timeiTypical time from the deadline to the funder's decision.—
Project durationiHow long the funded work is expected to run.—
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Cooperative agreement
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.0%
Funding pooliThe total budget available across all awards in this round.$39.9M
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Last verified: 24 Jul 2026Source: commonfund.nih.gov