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Program

Complement Animal Research In Experimentation (Complement-ARIE)

Funds human-based alternatives to animal testing through investments in replacement methodologies.

NIH Common FundUnited StatesCooperative agreement
About

Complement Animal Research in Experimentation (Complement-ARIE) is a Human-based New Approach Methodologies initiative within NIH Common Fund’s Office of the Director and advances research methods that are intended to model human biology more accurately than traditional animal-only models. It was approved by the NIH Council of Councils on January 25, 2024, and moved into first full-funding status …

Industries covered
AIBiotechMedtech
Grants under Complement Animal Research In Experimentation (Complement-ARIE)

Each grant below is a distinct funding opportunity with its own eligibility, scope, and deliverables.

Complement-ARIE — Open Funding (Seed)
Open

Supports development of human-based new approach methodologies replacing animal models in relevant research.

$39.9M pool·Rolling submission
Last verified: 29 May 2026Source: commonfund.nih.gov