NIH R21 Exploratory Research Grant — Parent PA
Supports exploratory developmental research through recurring NIH parent mechanisms in the United States.
The NIH R21 Exploratory/Developmental Research Project Grant supports high-risk, novel research ideas that lack the preliminary data base typically required for an R01. Two parent announcements cover open R21 submissions: PA-25-304 (Clinical Trial Not Allowed) and PA-25-306 (Clinical Trial Required), both released December 18, 2024, and active through January 8, 2028. New application deadlines are…
Exploratory and developmental biomedical research with high-risk, novel hypotheses across any NIH Institute or Center area, on a three-cycle annual submission schedule.
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