National Institutes of Health logo
NIH SBIR

NIH SBIR Phase I (Omnibus)

Funds United States small businesses advancing biomedical and behavioral-health innovations through early technical validation.

OpenNational Institutes of HealthUnited StatesDeep-tech · adjacent
Apply on funder portal
About

The NIH SBIR Phase I Omnibus is the National Institutes of Health's flagship non-dilutive feasibility grant for U.S. small businesses working on biomedical, behavioral-health, or health-services innovation. Issued under activity code R43, Phase I awards are capped at $306,872 in total costs (direct costs, indirect costs, and a permitted profit fee of up to 7%) and are intended to fund six to twelv…

What this grant funds

Any biomedical, behavioral, or health-services R&D aligned to the mission of one of NIH's 27 institutes and centers. Topic priorities are published by each IC; the omnibus parent NOFO is investigator-initiated within those priorities.

Key facts
CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.Multiple per year
Next deadlineiThe next date applications are due. Rolling means you can apply any time.5 Sept 2026
Decision timeiTypical time from the deadline to the funder's decision.32 weeks
Project durationiHow long the funded work is expected to run.1–6 months
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.0%
Funding pooliThe total budget available across all awards in this round.$220M
Funding analytics

Sign up free to see the funding breakdown

Create free accountSign in
Industries

Sign up free to see the industries in scope

Create free accountSign in
Eligibility criteria

Sign up free to see the full eligibility

Create free accountSign in
Application process

Sign up free to see how to apply

Create free accountSign in
What you have to submit

Sign up free to see what you submit

Create free accountSign in
How they score you

Sign up free to see how they score you

Create free accountSign in
Timeline

Sign up free to see the timeline

Create free accountSign in
Where founders trip up

Sign up free to see where teams trip up

Create free accountSign in
Last verified: 29 Jun 2026Source: grants.nih.gov