AISI Challenge Fund for AI Safety and Security Research
Funds AI safety and security research, up to £200,000 per project.
The fund runs a multi-stage review process, giving applicants detailed application packs, clarification-question documents and cost guidance. It launched in March 2025, and the first round has already completed its review cycle; AISI expects further rounds as it expands its external research funding portfolio, though none is confirmed as currently open.
The AISI Challenge Fund backs work tackling the dangers posed by frontier AI models, sitting apart from AISI's narrower Alignment Project (stopping bad model behaviour) and its Systemic Safety programme (wider societal deployment risks). It wants proposals built around a specific, sharply scoped safety or security problem, with a clear plan and results that can actually be measured.
Sign up free to see the funding breakdown
Sign up free to see the industries in scope
Sign up free to see the full eligibility
Sign up free to see how to apply
Sign up free to see where teams trip up
Guides for this application
All guides →Government Grants for Startups: What Deeptech Founders Should Know
A practical guide to government grants for startups, including Grants.gov, SBIR/STTR, state programs, eligibility, fit, timelines, and when to apply.
Start hereTRL Levels Explained for Deeptech Founders
Learn what TRL levels mean, how to estimate technology readiness, and how TRL affects grants, EIC Accelerator, SBIR/STTR, funding stage, and application evidence.
Write proposalHow to Write a Grant Proposal Reviewers Can Score
Learn how to write a grant proposal around reviewer criteria, evidence, work packages, budget logic, and commercialization for deeptech and R&D funding.
Similar grants
Browse the directory →
SBO Security and Defence
🇧🇪FWO · Belgium
Funds strategic basic research in security and defense aligned with space, maritime, aviation, and cybersecurity priorities.
NSTDA Research Chair Grant
🇹🇭NSTDA · Thailand
Supports Thai research groups with long-term chair-backed project resources and visibility.
SPRIND Recoding Medicine Challenge — Stage 1
🇩🇪SPRIND · Germany
Funds teams that curate a valuable health dataset and prove its worth with a working AI application.
Computational Approaches to Curation at Scale for Biomedical Research Assets
🇺🇸NIH · United States
Funds computational methods that curate biomedical data at scale, so datasets and models become usable faster than hand-curation allows.
Infrastructure Innovation for Biological Research
🇺🇸NSF · United States
Funds new or radically improved research tools and methods for biology — bioinformatics, instrumentation and research methods.
Advancing Bioinformatics, Translational Bioinformatics and Computational Biology Research
NIH · United States
Funds new bioinformatics, computational biology, or AI methods that turn messy biomedical datasets into usable knowledge.