National Institute on Aging
Funds aging and dementia research through the National Institute on Aging, including investigator support, company routes, and aging-care programs.
The National Institute on Aging (NIA) is the NIH component that leads federal aging research. It is the second-largest NIH institute by budget, with an FY2026 enacted budget of about $4.53 billion, and its Division of Neuroscience holds most of the Alzheimer's disease and related dementias funding.
NIA backs basic science, translational work, and clinical studies across aging biology, Alzheimer's disease and related dementias, behavioral and social science, and geriatric clinical gerontology. Its routes include SBIR and STTR programs that support aging-focused companies, the AD/ADRD R01 and R21 lines, the Alzheimer's Drug-Development Program, Alzheimer's Disease Research Centers, and a small-business portfolio that provides about $150 million per year to aging-focused companies.
Applicants tend to do best when the proposal speaks directly to aging biology, dementia, or geriatric care and can show a clean path from discovery to translation or deployment. NIA's grant pages also point applicants to research divisions, funding policies and paylines, training, data sharing, and clinical-trial guidance, so it functions as a structured home for both academic and company-facing aging work.