Novel Small-Molecule Antivirals for Epidemic-Potential Pathogens
Funds small-molecule antivirals that expand preparedness and treatment options for future viral epidemics and pandemics.
Emerging and re-emerging viral infections threaten European and global health, and climate change is accelerating emergence. This Research and Innovation Action strengthens the EU medical-countermeasures ecosystem by advancing small-molecule prophylactic and therapeutic candidates against a single specified virus or virus group.
Projects should select and state one permitted target group, then di…
Develop novel or existing small-molecule antiviral candidates against exactly one permitted virus or virus group: Junin/Lassa; tick-borne encephalitis/Japanese encephalitis; Andes/Hantaan/Sin Nombre; Hendra; Enterovirus D68; or Venezuelan equine encephalitis. Cover discovery, optimisation, antiviral activity and resistance, animal or organoid models, GMP batches and first-in-human safety where appropriate. Antibodies and antibody-derived proteins are excluded.
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