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Horizon Europe Cluster 1 — Health (HLTH)

AI Predictive Biomarkers for Chronic Diseases

Funds trustworthy AI biomarker methods that predict chronic-disease progression and treatment response for personalised care.

ScheduledEuropean CommissionEU

Many clinically relevant biomarkers have not reached practice because chronic diseases are heterogeneous and a single-biomarker approach cannot reliably predict progression or treatment response. This two-stage Research and Innovation Action supports collaborative development of multimodal predictive biomarkers using established AI methods rather than novel AI from scratch.

Projects should map av

Adapt established AI methods to combine existing and candidate multimodal biomarkers with longitudinal clinical studies and Real-World Data for chronic non-communicable diseases excluding cancer. Develop trustworthy, accurate, reliable and reproducible predictive biomarkers, validate them in independent cohorts and clinical studies, and provide clinician-facing decision tools, GDPR-compliant data practices and regulatory and exploitation pathways.

CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.One-off
Next deadlineiThe next date applications are due. Rolling means you can apply any time.13 Apr 2027
Decision timeiTypical time from the deadline to the funder's decision.22 weeks
Project durationiHow long the funded work is expected to run.
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.0%
Funding pooliThe total budget available across all awards in this round.€44.2M

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Last verified: 25 Aug 2026Funder reference: HORIZON-HLTH-2027-02-TOOL-01-TWO-STAGESource: ec.europa.eu