ARPA-H Program ISOs (topic-specific)
Funds United States health initiatives through topic-focused pathways across multiple mission areas and agencies.
ARPA-H Program Innovative Solution Openings (ISOs) are the agency's time-limited, topic-focused solicitations in which individual ARPA-H program managers define a specific transformational health challenge and invite proposals to address it. Each Program is a multi-year, multi-awardee effort typically deploying $50M to $300M total across 4 to 15 awardees over three to five years. Individual award …
Specific health technology challenges. Current open Program ISOs include: 1-CURE (universal radiotherapy), BoSS (biostabilization), CIRCLE (critical-illness immune control), Delphi (self-monitoring ecosystems), HEARING (AI-driven hearing neurotechnology), IGoR (intelligent research generator), STOMP (microplastics targeting).
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