Genesis Mission — DE-FOA-0003612
Supports national artificial intelligence and science challenge response through sustained development grants.
The Genesis Mission FY2026 Request for Application (RFA DE-FOA-0003612), posted March 17, 2026, made $293 million available through the U.S. Department of Energy's Office of Science to apply artificial intelligence to 26 national science and technology challenges. The 26 challenges, announced February 12, 2026, by Under Secretary for Science Darío Gil, span advanced manufacturing, biotechnology, c…
26 challenges spanning advanced manufacturing, biotechnology, critical materials, nuclear energy, and quantum information science.
Sign up free to see the funding breakdown
Sign up free to see the industries in scope
Sign up free to see the full eligibility
Sign up free to see how to apply
Sign up free to see what you submit
Sign up free to see the timeline
Guides for this application
All guides →Grants for Biotech Startups: NIH, NSF, SBIR/STTR, and Non-Dilutive Funding
A practical guide to grants for biotech startups, including NIH SBIR/STTR, NSF, translational funding, evidence, regulatory readiness, and budgets.
DocumentsGrant Work Plan Template: Work Packages, Gantt, Milestones, and Risks
Use this grant work plan template to structure work packages, tasks, owners, deliverables, Gantt timing, dependencies, and risk registers.
Submit & reportSAM.gov Registration and UEI Guide for Federal Grant Applicants
Learn how SAM.gov registration, UEI numbers, Grants.gov accounts, organization profiles, workspace roles, and renewal timing fit together.
BudgetBudget Narrative Example for Grant Proposals
See how to write a grant budget narrative with line-item examples, a template structure, weak vs strong wording, and reviewer-facing cost logic.
More from DOE
All grants from this funder →Annual Recurring University Training and Research
🇺🇸DOE · United States
Funds early-stage research and training for engineering and science students at U.S. colleges, awarded every year by DOE's national energy lab.
DOE SBIR Phase I
🇺🇸DOE · United States
Funds U.S. for-profit small businesses establishing technical feasibility of innovative technologies across DOE priority areas including advanced manufacturing, critical materials, and quantum information science.
DOE SBIR Phase II
🇺🇸DOE · United States
Funds U.S. small businesses advancing energy and science technologies from proven feasibility into prototype development through DOE's Phase II SBIR award.
Advanced Nuclear Energy Licensing Cost-Share Grant Program
🇺🇸DOE · United States
Funds the cost-shared work of licensing advanced nuclear reactor designs, open to companies, universities, nonprofits and local and tribal governments.
Community Power Accelerator Prize
🇺🇸DOE · United States
Pays U.S. community solar developers cash across three phases from a $10 million pool.
Community Power Accelerator Prize — Round 2
🇺🇸DOE · United States
Pays U.S. community solar developers cash across three phases from a $10 million pool.
Similar grants
Browse the directory →
Lightweight and Propulsion Materials — R&D
🇺🇸DOE TTO · United States
Supports teams advancing transport and mobility materials through applied innovation and manufacturing.
MEP Center State Competition
🇺🇸NIST MEP · United States
Supports a designated state through a dedicated MEP Center to provide manufacturing technical assistance to small and medium firms.
Tech Hubs Implementation Grants
🇺🇸EDA · United States
Offers research teams and institutions for Tech Hubs Implementation Grants in artificial intelligence, manufacturing, and semiconductors.
NSF Regional Innovation Engines — Competition 3
🇺🇸NSF TIP · United States
Funds regional innovation ecosystems in the United States to build practical manufacturing and technology pathways.
DHS LRBAA 24-01 — Research
🇺🇸DHS S&T · United States
Supports organizations pursuing homeland security innovation in AI, detection, screening, and resilience through DHS open submissions.
DARPA DSO Office-wide BAA
🇺🇸DARPA · United States
Funds United States defense science ideas with high-security relevance across devices, systems, and cross-domain innovation.