The Genesis Mission: Transforming Science and Energy with AI
Supports AI for science progress from early concept stages toward national-scale implementation.
The Genesis Mission: Transforming Science and Energy with AI (DE-FOA-0003612) is the DOE Office of Science's flagship artificial intelligence initiative for FY2026, covering AI applications across all five primary program offices: Advanced Scientific Computing Research (ASCR), Basic Energy Sciences (BES), Biological and Environmental Research (BER), Fusion Energy Sciences (FES), and High Energy Ph…
Artificial intelligence applied to scientific discovery and energy research across DOE Office of Science program offices including ASCR, BES, BER, FES, and HEP.
Sign up free to see the funding breakdown
Sign up free to see the industries in scope
Sign up free to see the full eligibility
Sign up free to see how to apply
Sign up free to see what you submit
Sign up free to see the timeline
Guides for this application
All guides →Grants for Biotech Startups: NIH, NSF, SBIR/STTR, and Non-Dilutive Funding
A practical guide to grants for biotech startups, including NIH SBIR/STTR, NSF, translational funding, evidence, regulatory readiness, and budgets.
DocumentsGrant Work Plan Template: Work Packages, Gantt, Milestones, and Risks
Use this grant work plan template to structure work packages, tasks, owners, deliverables, Gantt timing, dependencies, and risk registers.
Submit & reportSAM.gov Registration and UEI Guide for Federal Grant Applicants
Learn how SAM.gov registration, UEI numbers, Grants.gov accounts, organization profiles, workspace roles, and renewal timing fit together.
Find grantsGovernment Grants for Startups: What Deeptech Founders Should Know
A practical guide to government grants for startups, including Grants.gov, SBIR/STTR, state programs, eligibility, fit, timelines, and when to apply.
More from DOE SC
All grants from this funder →The Genesis Mission: AI for Science and Energy
🇺🇸DOE SC · United States
Provides research teams and institutions for The Genesis Mission: AI for Science and Energy in artificial intelligence, energy systems, and quantum systems.
Continuation of Solicitation for the DOE Office of Science Financial Assistance Program
🇺🇸DOE SC · United States
Supports unsolicited basic research proposals across all Office of Science thematic areas in the United States.
DOE Early Career Research Program
🇺🇸DOE SC · United States
Funds research teams and institutions for DOE Early Career Research in energy systems, artificial intelligence, and quantum systems.
DOE Energy Frontier Research Centers
🇺🇸DOE SC · United States
Backs research teams and institutions for DOE Energy Frontier Research Centers in energy systems, materials science, and quantum systems.
Energy Frontier Research Centers — 8th Class
🇺🇸DOE SC · United States
Supports multidisciplinary research centers tackling fundamental energy science grand challenges.
FY 2026 Continuation of Solicitation for the Office of Science Financial Assistance Program
🇺🇸DOE SC · United States
Funds DOE Office of Science research in computing, energy sciences, biology, fusion, high-energy and nuclear physics, and isotopes — open to any applicant type.
Similar grants
Browse the directory →
Genesis Mission AI FOA — Phase I and Phase II (FES)
🇺🇸DOE FES · United States
Supports AI-enabled fusion and plasma research with continuation pathways for strong performers.
NASA ROSES — Science Mission Directorate Omnibus
🇺🇸NASA · United States
Funds a broad United States NASA Science Mission Directorate package across multiple science and mission areas.
AFRI Foundational and Applied Science
🇺🇸USDA NIFA · United States
Supports agriculture innovation across plant health, bioenergy, food safety, and rural systems through USDA research grants and extension.
Technology Transfer Assistance Grant (TTAG)
🇺🇸AEDC · United States
Matching grant for transferring innovative technology into Arkansas-based enterprises.
Michigan Translational Research And Commercialization
🇺🇸MEDC · United States
Funds Michigan translation projects moving university research toward commercialization through innovation hubs.
McKinney Innovation Fund — Expansion Grant
🇺🇸McKinney EDC · United States
Offers performancebased grant for growthstage McKinney tech companies hitting ARR or raised through the McKinney Innovation Fund Expansion Grant.