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Funder · Federal agency

DOE Office of Science

Runs DOE Office of Science, stewarding United States national laboratories and core physical science programs.

United States
Key stats
Annual funding-
Programs16
Active grants3
Total grants10
About

The DOE Office of Science, usually shortened to DOE SC, is the United States' largest supporter of basic research in the physical sciences and operates under the Department of Energy. It stewards ten national laboratories and runs major user facilities, from particle accelerators and X-ray light sources to exascale computing centers.

Its funding reaches universities, national laboratories, and so…

Programs & grants under this funder
FY 2026 Continuation of Solicitation for the Office of Science Financial Assistance Program

Funds DOE Office of Science research in computing, energy sciences, biology, fusion, high-energy and nuclear physics, and isotopes — open to any applicant type.

1 grant
FY 2026 Continuation of Solicitation for the Office of Science Financial Assistance Program
Between cycles
$500M pool
DOE Microelectronics Centers / SCAMP Strategic Centers

Supports research teams and universities in United States by guiding innovation from prototype work to stronger buyer demand.

NNSA Minority Serving Institution Partnership Program (MSIPP)

Supports workforce pathways in Tribal Colleges and minority-serving institutions through partnerships.

NNSA Stewardship Science Academic Alliances (SSAA)

Funds university programs strengthening stewardship science and workforce pathways for national missions.

DOE SBIR/STTR TABA / Phase II Sequential

Offers Department of Energy technology acceleration support for advanced manufacturing demonstrations.

DOE ARDAP — Accelerator R&D and Production

Helps DOE ARDAP Accelerator scientific advancement and Production for Accelerator technology scientific advancement.

1 grant
Research Opportunities in Accelerator Stewardship and Accelerator Development
Between cycles
$11.5M pool
DOE Office of Science Early Career Research Program

Funds early-career scientists in physical sciences across universities and United States. laboratories.

1 grant
DOE Early Career Research Program
Between cycles
$145M pool
Energy Frontier Research Centers (EFRC)

Helps Energy Frontier Research Centers for Four-year centers funding multidisciplinary teams on grand challenges in energy science.

1 grant
Energy Frontier Research Centers — 8th Class
Between cycles
- pool
DOE Office of Science Energy Frontier Research Centers (EFRCs)

Funds collaborative energy science centers with broad institutional participation and shared goals.

1 grant
DOE Energy Frontier Research Centers
Between cycles
- pool
DOE Office of Science Financial Assistance Program (Umbrella FOA)

Helps DOE Office of Science Financial Assistance Program for unsolicited basic research proposals across all SC program offices.

1 grant
Continuation of Solicitation for the DOE Office of Science Financial Assistance Program
Open
- pool
The Genesis Mission: Transforming Science and Energy with AI

Funds science and energy applications using AI across Office of Science programs in the United States.

2 grants
The Genesis Mission: AI for Science and Energy
Open
- pool
The Genesis Mission: Transforming Science and Energy with AI
Open
- pool
INCITE — Innovative and Novel Computational Impact on Theory and Experiment

Helps INCITE Innovative and Novel Computational Impact on Theory and Experiment for Large-scale allocations of exascale supercomputer time on Aurora and Frontier.

1 grant
INCITE — Proposals
Between cycles
- pool
INFUSE — Innovation Network for Fusion Energy

Provides vouchers for private fusion firms to use United States. laboratory expertise and facilities.

DOE Office of Science Continuation of Solicitation for Financial Assistance

Supports high-value research proposals across Office of Science divisions in the United States.

1 grant
DOE Office of Science Open Solicitation
Closed
- pool
DOE SBIR Phase I

Funds proof-of-concept research by small businesses in energy, manufacturing, and quantum innovation.

DOE SBIR Phase II

Backs second extension for further development in innovation through the DOE II.

Parent entityUS Department of Energy
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