The Genesis Mission: Transforming Science and Energy with AI

The Genesis Mission: Transforming Science and Energy with AI is DOE Office of Science's FY2026 AI-for-science and energy initiative. It spans the SC portfolio and is set up as a one-off solicitation rather than a standing annual call. The program is a grant route with a phased process, a May 2026 gate, and a final application deadline of December 17, 2026. The captured record points to U.S. universities and research organizations rather than individuals or companies, and the public materials in hand do not give a central award size. Applicants should read it as a mission-driven AI competition across DOE science and energy priorities, not as a general-purpose AI program. The strongest fit is a research team that can tie AI methods to a concrete Office of Science problem and show direct relevance to the DOE mission. Because the funding is phased, a team needs a crisp first-stage concept and a path to a credible full proposal.

Each grant below is a distinct funding opportunity with its own eligibility, scope, and deliverables.