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NIH Research Project Grant

NIH R01 Research Project Grant — Parent PA

Supports investigator-initiated research in the United States through continuous grant opportunities.

Between cyclesNational Institutes of HealthUnited States
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About

The NIH R01 Research Project Grant is the primary investigator-initiated funding mechanism at the National Institutes of Health, the largest public funder of biomedical research in the world. Two active parent announcements govern open R01 submissions: PA-25-301 (Clinical Trial Not Allowed) and PA-25-305 (Clinical Trial Required), both issued December 18, 2024, open January 5, 2025, and active thr…

What this grant funds

Investigator-initiated biomedical and behavioral research projects across any NIH Institute or Center topic area, submitted on a three-cycle annual schedule.

Key facts
CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.Multiple per year
Next deadlineiThe next date applications are due. Rolling means you can apply any time.5 Oct 2026
Decision timeiTypical time from the deadline to the funder's decision.—
Project durationiHow long the funded work is expected to run.—
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.0%
Funding pooliThe total budget available across all awards in this round.—
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Last verified: 30 Jul 2026Source: grants.nih.gov