Focused Antibiotics
Funds United Kingdom and global teams redesigning antibiotic strategies while preserving gut microbiome health.
Wellcome Leap's Focused Antibiotics program is a newly announced $50 million initiative targeting one of medicine's most stubborn tradeoffs: antibiotics that kill the target pathogen also devastate the gut microbiome, causing collateral harm that contributes to long-term health consequences. The program challenges performer teams to reformulate existing antibiotics to spare the gut microbiome with…
Reformulation of existing antibiotics targeting urinary tract infections, lower respiratory tract infections, and acute otitis media to eliminate gut microbiome collateral damage while maintaining treatment efficacy.
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