NIH STTR

NIH STTR (Small Business Technology Transfer) carries 0.45% of NIH's extramural R&D budget — roughly $170M annually. It runs alongside SBIR with the same award sizes ($323K Phase I, $2.15M Phase II) and the same Phase I/Phase II/Fast-Track ladder. The defining difference: STTR requires formal partnership with a non-profit research institution (typically a university). At least 40% of the work must be done by the small business; at least 30% by the research-institution partner. Unlike SBIR, STTR does not allow majority-VC-owned applicants. The principal investigator may be employed by either the small business or the research-institution partner. STTR is designed to bridge the academic-to-commercial translation gap that pure SBIR cannot.

Each grant below is a distinct funding opportunity with its own eligibility, scope, and deliverables.