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NIH Pragmatic Trials Conducted in Health Care Systems

Funds large pragmatic or implementation trials that test how well interventions work inside real health care settings.

National Institutes of HealthGlobalCooperative agreement

A treatment that works in a research clinic does not always work in a busy emergency department or an under-resourced primary care practice. This notice funds finding out in the settings that actually matter to patients, clinicians and the people who pay for care.

Two kinds of trial are supported. Pragmatic trials that test whether an intervention is effective in routine clinical care. And implem

Each grant below is a distinct funding opportunity with its own eligibility, scope, and deliverables.

Last verified: 27 Aug 2026Source: www.grants.gov